验证数据展示
经过测试的应用
| Positive WB detected in | A549 cells, HEK-293 cells, human placenta tissue, mouse kidney tissue, mouse liver tissue, rat kidney tissue, rat liver tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:8000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| WB | See 1 publications below |
产品信息
29784-1-AP targets MPZL1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 文献引用应用 | WB |
| 经测试反应性 | human, mouse, rat |
| 文献引用反应性 | human |
| 免疫原 |
CatNo: Ag31532 Product name: Recombinant human MPZL1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 36-162 aa of BC007881 Sequence: SALEVYTPKEIFVANGTQGKLTCKFKSTSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYVVEKENLPV 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | myelin protein zero-like 1 |
| 别名 | PZR1b, PZR, Protein zero-related, Protein zero related, Myelin protein zero-like protein 1 |
| 计算分子量 | 29 kDa |
| 观测分子量 | 32 kDa |
| GenBank蛋白编号 | BC007881 |
| 基因名称 | MPZL1 |
| Gene ID (NCBI) | 9019 |
| RRID | AB_3669695 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | O95297 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Myelin protein zero-like 1 (MPZL1, also known as PZR) is a transmembrane glycoprotein that promotes the migration of hepatocellular carcinoma cells and is involved in extracellular matrix-induced signal transduction (PMID: 16702974; 8912526). Phosphorylated MPZL1 was linked to the regulation of cell adhesion and migration (PMID: 24296779; 18378677; 12410637). The expression levels of MPZL1 were also associated with malignant features of ovarian cancer (PMID: 31233194).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for MPZL1 antibody 29784-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
