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验证数据展示

  • WB analysis using 86033-1-RR (same clone as 86033-1-PBS)

    WB analysis using 86033-1-RR (same clone as 86033-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86033-1-RR (MPRIP antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86033-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse brain using 86033-1-RR (same clone as 86033-1-PBS)

    IF Staining of mouse brain using 86033-1-RR (same clone as 86033-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse brain tissue using MPRIP antibody (86033-1-RR, Clone: 250643B2 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 86033-1-PBS in a different storage buffer formulation.

MPRIP Recombinant monoclonal antibody, PBS Only

MPRIP Uni-rAb® Recombinant Antibody for WB, IF-P, Indirect ELISA
Cat No. 86033-1-PBS

产品说明书

CloneNo. 250643B2

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IF-P, Indirect ELISA

别名

M RIP, MRIP, M-RIP, Myosin phosphatase Rho-interacting protein, p116Rip

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy MPRIP Ready-To-Use IHC Kit. MPRIP primary antibody included.

产品信息

86033-1-PBS targets MPRIP in WB, IF-P, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IF-P, Indirect ELISA Application Description
经测试反应性 human
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 myosin phosphatase Rho interacting protein
别名 M RIP, MRIP, M-RIP, Myosin phosphatase Rho-interacting protein, p116Rip
计算分子量 117 kDa
观测分子量 140 kDa
GenBank蛋白编号NM_015134
基因名称 MPRIP
Gene ID (NCBI) 23164
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ6WCQ1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

MPRIP, also named as KIAA0864, MRIP, RHOIP3 and p116Rip, is required for the regulation of the actin cytoskeleton by RhoA and ROCK1. MRPIP targets myosin phosphatase to the actin cytoskeleton. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells. The antibody recognizes the C-term of isoform2 and isoform3 of MPRIP.

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