验证数据展示
产品信息
68370-1-PBS targets MORC3 in WB, Indirect ELISA applications and shows reactivity with Human, mouse samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | Human, mouse |
免疫原 | MORC3 fusion protein Ag21867 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | MORC family CW-type zinc finger 3 |
别名 | KIAA0136, MORC3, NXP2, ZCW5, ZCWCC3 |
计算分子量 | 939 aa, 107 kDa |
观测分子量 | 130 kDa |
GenBank蛋白编号 | BC132731 |
基因名称 | MORC3 |
Gene ID (NCBI) | 23515 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | Q14149 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
MORC3, also named as MORC family CW-type zinc finger protein 3 or NXP2, is a 939 amino acid protein, which contains 1 CW-type zinc finger. MORC3 localizes in the nucleus and are expressed in heart, placenta, skeletal muscle, brain, pancreas, lung, liver, but not kidney. MORC3 as Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism. Sumoylated MORC3-NBs can also associate with PML-NBs and recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity. It may be required for influenza A transcription during viral infection. The calculated molecular weight of MORC3 is a 107 kDa, but the Sumoylated MORC3 protein is about 130 kDa.