MORC3 Monoclonal antibody, PBS Only

MORC3 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 68370-1-PBS

产品说明书

CloneNo. 1E1E1

宿主/亚型

Mouse / IgG1

种属反应性

Human, mouse

应用

WB, Indirect ELISA

KIAA0136, MORC3, NXP2, ZCW5, ZCWCC3

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存


产品信息

68370-1-PBS targets MORC3 in WB, Indirect ELISA applications and shows reactivity with Human, mouse samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human, mouse
免疫原

CatNo: Ag21867

Product name: Recombinant human MORC3 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 590-939 aa of BC132731

Sequence: DHDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST

种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 MORC family CW-type zinc finger 3
别名 KIAA0136, MORC3, NXP2, ZCW5, ZCWCC3
计算分子量 939 aa, 107 kDa
观测分子量130 kDa
GenBank蛋白编号BC132731
基因名称 MORC3
Gene ID (NCBI) 23515
偶联类型 Unconjugated
形式Liquid
纯化方式Protein G purification
UNIPROT IDQ14149
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

MORC3, also named as MORC family CW-type zinc finger protein 3 or NXP2, is a 939 amino acid protein, which contains 1 CW-type zinc finger. MORC3 localizes in the nucleus and are expressed in heart, placenta, skeletal muscle, brain, pancreas, lung, liver, but not kidney. MORC3 as Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism. Sumoylated MORC3-NBs can also associate with PML-NBs and recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity. It may be required for influenza A transcription during viral infection. The calculated molecular weight of MORC3 is a 107 kDa, but the Sumoylated MORC3 protein is about 130 kDa.

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