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验证数据展示

  • WB analysis using 87552-1-RR (same clone as 87552-1-PBS)

    WB analysis using 87552-1-RR (same clone as 87552-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 87552-1-RR (MMP7 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 87552-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon using 87552-1-RR (same clone as 87552-1-PBS)

    IHC staining of human colon using 87552-1-RR (same clone as 87552-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 87552-1-RR (MMP7 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 87552-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon using 87552-1-RR (same clone as 87552-1-PBS)

    IHC staining of human colon using 87552-1-RR (same clone as 87552-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 87552-1-RR (MMP7 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 87552-1-PBS in a different storage buffer formulation.

MMP7 Recombinant monoclonal antibody, PBS Only

MMP7 Uni-rAb® Recombinant Antibody for WB, IHC, Indirect ELISA
Cat No. 87552-1-PBS

产品说明书

CloneNo. 252985B7

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

EC:3.4.24.23, Matrilysin, Matrin, Matrix metalloproteinase 7, Matrix metalloproteinase-7

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

87552-1-PBS targets MMP7 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag0550

Product name: Recombinant human MMP7 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-100 aa of BC003635

Sequence: MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSHVIEIMQKPRCGVPDVAEYSLFPN

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 matrix metallopeptidase 7 (matrilysin, uterine)
别名 EC:3.4.24.23, Matrilysin, Matrin, Matrix metalloproteinase 7, Matrix metalloproteinase-7
计算分子量 29 kDa
观测分子量 27-30 kDa
GenBank蛋白编号BC003635
基因名称 MMP7
Gene ID (NCBI) 4316
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP09237
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Matrix metalloproteinase-7 (MMP-7)/ matrilysin is a member of the MMP family, but is structurally different from the other MMPs by virtue of the absence of a conserved COOH-terminal protein domain. MMPs are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and cancer metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP-7 degrades proteoglycans, fibronectin, elastin and casein, and is involved in wound healing, tumor progression, pulmonary fibrosis, and development of choroidal neovascularization in age-related macular degeneration. The expression of MMP-7 is increased in most tumors.

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