验证数据展示
发表文章中的应用
WB | See 1 publications below |
产品信息
55340-1-AP targets MMP10 in WB, ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | ELISA Application Description |
文献引用应用 | WB |
经测试反应性 | human, mouse |
文献引用反应性 | human |
免疫原 | Peptide 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | matrix metallopeptidase 10 (stromelysin 2) |
别名 | Matrix metalloproteinase 10, MMP 10, MMP10, SL 2, STMY2, Stromelysin 2, Transin 2 |
计算分子量 | 54 kDa |
观测分子量 | 52 kDa |
GenBank蛋白编号 | NM_002425 |
基因名称 | MMP10 |
Gene ID (NCBI) | 4319 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P09238 |
储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
储存条件 | Store at -20°C. Aliquoting is unnecessary for -20oC storage. |
背景介绍
MMP10, also named as STMY2, Transin-2, MMP-10, SL-2 and Stromelysin-2, belongs to the peptidase M10A family. It can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. MMP10 activates procollagenase.Western blot against MMP-10 revealed bands at a molecular weight of about 56 and 42 kDa in serum samples,and the bands with molecular weights of about 42 kDa may be the active forms of MMP-10(PMID:20215736). The expression profile of MMP-10 in several human tumors, coupled with broadsubstrate specificity and expression in several stages of the tumorigenic process suggests MMP-10 as a potential tumor marker and a predictor of clinical behavior, and supports MMP-10 inhibition as a valid therapeutic strategy(PMID:15720804).This antibody is specific to MMP10.