MMP10 Polyclonal antibody

MMP10 Polyclonal Antibody for ELISA
Cat No. 55340-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

ELISA and More (1)

Matrix metalloproteinase 10, MMP 10, MMP10, SL 2, STMY2, Stromelysin 2, Transin 2

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
规格: 

-/ -


发表文章中的应用

WBSee 1 publications below

产品信息

55340-1-AP targets MMP10 in WB, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 ELISA Application Description
文献引用应用WB
经测试反应性 human, mouse
文献引用反应性human
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 matrix metallopeptidase 10 (stromelysin 2)
别名 Matrix metalloproteinase 10, MMP 10, MMP10, SL 2, STMY2, Stromelysin 2, Transin 2
计算分子量 54 kDa
观测分子量 52 kDa
GenBank蛋白编号NM_002425
基因名称 MMP10
Gene ID (NCBI) 4319
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP09238
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Aliquoting is unnecessary for -20oC storage.

背景介绍

MMP10, also named as STMY2, Transin-2, MMP-10, SL-2 and Stromelysin-2, belongs to the peptidase M10A family. It can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. MMP10 activates procollagenase.Western blot against MMP-10 revealed bands at a molecular weight of about 56 and 42 kDa in serum samples,and the bands with molecular weights of about 42 kDa may be the active forms of MMP-10(PMID:20215736). The expression profile of MMP-10 in several human tumors, coupled with broadsubstrate specificity and expression in several stages of the tumorigenic process suggests MMP-10 as a potential tumor marker and a predictor of clinical behavior, and supports MMP-10 inhibition as a valid therapeutic strategy(PMID:15720804).This antibody is specific to MMP10.

发表文章

SpeciesApplicationTitle
humanWB

Cancer Cell Int

A novel disulfide death-related genes prognostic signature identifies the role of IPO4 in glioma progression

Authors - HaoYuan Wu
Loading...