验证数据展示
产品信息
Biotin-83242-4 targets MLLT1 in applications and shows reactivity with human samples.
| 经测试应用 | Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag34210 Product name: Recombinant human MLLT1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 130-480 aa of BC148806 Sequence: EFRYKLLRAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCS 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 |
| 别名 | ENL, LTG19, MLLT 1, Protein ENL, YEATS1 |
| 计算分子量 | 62 kDa |
| GenBank蛋白编号 | BC148806 |
| 基因名称 | MLLT1 |
| Gene ID (NCBI) | 4298 |
| RRID | AB_3746768 |
| 偶联类型 | Biotin |
| 最大激发/发射波长 | - |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q03111 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
MLLT1 encodes a chromatin reader in the super elongation complex that promotes transcriptional elongation by binding acetylated and crotonylated histones. Through its YEATS domain, it shows strong preference for H3K27cr, linking histone acylation marks to increased RNA polymerase II pause-site release and gene expression. The protein is found in the nucleus, nucleoplasm, cytosol, and fibrillar center.
