验证数据展示
经过测试的应用
| Positive WB detected in | COLO 320 cells, mouse small intestine tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
32828-1-AP targets MEP1B in WB, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
Recombinant protein 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | meprin A, beta |
| 别名 | EC:3.4.24.63, Endopeptidase-2, Meprin A subunit beta, Meprin B, N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta |
| 计算分子量 | 80 kDa |
| 观测分子量 | 100 kDa |
| GenBank蛋白编号 | NM_001308171.1 |
| 基因名称 | MEP1B |
| Gene ID (NCBI) | 4225 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q16820 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
MEP1B, also known as meprin A subunit beta, is a gene that encodes a metalloprotease belonging to the Astacins family of zinc endopeptidases. The MEP1B gene is highly expressed in the small intestine and duodenum, and it is also expressed in the kidneys, leukocytes, and certain cancer cells. MEP1B encodes a metalloprotease that plays a key role in the hydrolysis of various substrates, including collagen, laminin, and elastin, which are major components of the extracellular matrix. This function is crucial for tissue development, repair, and remodeling.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for MEP1B antibody 32828-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
