M-CSF Polyclonal antibody

M-CSF Polyclonal Antibody for ELISA
Cat No. 14779-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human and More (1)

应用

ELISA and More (3)

Macrophage colony-stimulating factor 1, M CSF, Lanimostim, CSF-1, CSF1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
规格: 

-/ -


产品信息

14779-1-AP targets M-CSF in WB, IF, ELISA, Cell treatment applications and shows reactivity with human samples.

经测试应用 ELISA Application Description
文献引用应用WB, IF, Cell treatment
经测试反应性 human
文献引用反应性human, mouse
免疫原 M-CSF fusion protein Ag6294 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 colony stimulating factor 1 (macrophage)
别名 Macrophage colony-stimulating factor 1, M CSF, Lanimostim, CSF-1, CSF1
计算分子量 60 kDa
观测分子量 70 kDa
GenBank蛋白编号BC021117
基因名称 M-CSF
Gene ID (NCBI) 1435
RRIDAB_10643241
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP09603
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Colony stimulating factor-1 (CSF-1) is a homodimeric glycoprotein that humorally regulates the proliferation and differentiation of mononuclear phagocytic cells and locally regulates cells of the female reproductive tract. Alternative splicing of the human CSF-1 mRNA leads to alternative expression of the CSF-1 homodimer as a secreted glycoprotein or as a membrane-spanning molecule with cell surface biological activity. CSF-1 is predominantly secreted as highly sulfated species of 375- and 250-kDa with a smaller amount of a 100-kDa species. The three predominant CSF-1 species were shown to be an 80-kDa homodimer, an 80-kDa/50-kDa heterodimer, and a 50-kDa homodimer. (PMID: 1733926) This antibody could recognieze 60 kDa, 48 kDa, 29 kDa isoforms.

发表文章

SpeciesApplicationTitle
mouseWB

J Control Release

Chemoattractants driven and microglia based biomimetic nanoparticle treating TMZ-resistant glioblastoma multiforme.

Authors - Sai Qiao
mouseWB,Cell treatment

J Nanobiotechnology

Biomimetic GBM-targeted drug delivery system boosting ferroptosis for immunotherapy of orthotopic drug-resistant GBM.

Authors - Bao Liu
WB

Biomed Pharmacother

Anti-osteoporotic effects of alisol C 23-acetate via osteoclastogenesis inhibition.

Authors - Xiaokang Jia
humanWB

Int J Biol Sci

Macrophage Colony-stimulating Factor Mediates the Recruitment of Macrophages in Triple negative Breast Cancer.

Authors - Xiaoqing Lu
human,mouseWB

Invest Ophthalmol Vis Sci

CSF1/CSF1R-mediated Crosstalk Between Choroidal Vascular Endothelial Cells and Macrophages Promotes Choroidal Neovascularization.

Authors - Yamei Zhou
mouseWB

Front Physiol

Heat Stress Modulates a Placental Immune Response Associated With Alterations in the Development of the Fetal Intestine and Its Innate Immune System in Late Pregnant Mouse.

Authors - Huiduo Guo
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