验证数据展示
经过测试的应用
| Positive WB detected in | HEK-293 cells, COLO 320 cells, HeLa cells, HepG2 cells |
| Positive IF/ICC detected in | HepG2 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:10-1:100 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
20080-1-AP targets MAS1L in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, IF/ICC, ELISA Application Description |
| 文献引用应用 | WB, IHC, IF |
| 经测试反应性 | human |
| 文献引用反应性 | human, rat |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | MAS1 oncogene-like |
| 别名 | MAS L, Mas related G protein coupled receptor MRG, MAS1L-Specific, MRG, MAS1-like |
| 计算分子量 | 42 kDa |
| 观测分子量 | 42 kDa |
| GenBank蛋白编号 | NM_052967 |
| 基因名称 | MAS1L |
| Gene ID (NCBI) | 116511 |
| RRID | AB_10665372 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P35410 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
MAS1L, also named MRG, belongs to the G-protein coupled receptor 1 family and Mas subfamily. The antibody is specific to MAS1L.
实验方案
| Product Specific Protocols | |
|---|---|
| IF protocol for MAS1L antibody 20080-1-AP | Download protocol |
| WB protocol for MAS1L antibody 20080-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Redox Biol Myeloid ACE2 protects against septic hypotension and vascular dysfunction through Ang-(1-7)-Mas-mediated macrophage polarization | ||
J Transl Med ApoE4 associated with severe COVID-19 outcomes via downregulation of ACE2 and imbalanced RAS pathway | ||
J Transl Med Mas receptor activation regulates the functional phenotype of myocardial macrophages through the Akt/Nrf2 signaling pathway to alleviate sepsis-induced cardiomyopathy. | ||
Phytother Res α-Mangostin Attenuates Blood Pressure and Reverses Vascular Remodeling by Balancing ACE/AT1R and ACE2/Ang-(1-7)/MasR Axes in Ang II-Infused Hypertensive Mice | ||
Br J Pharmacol Angiotensin-(1-7) alleviates intestinal barrier dysfunction and dysbiosis in mice with polymicrobial sepsis. | ||
J Ethnopharmacol Synergistic effect of constituent drugs of Baibutang on improving Yin-deficiency pulmonary fibrosis in rats |
