验证数据展示
产品信息
55244-1-PBS targets MAP4K2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, IHC, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | mitogen-activated protein kinase kinase kinase kinase 2 |
| 别名 | B lymphocyte serine/threonine-protein kinase, EC:2.7.11.1, GCK, MEKKK 2, Mitogen-activated protein kinase kinase kinase kinase 2 |
| 计算分子量 | 92 kDa |
| 观测分子量 | 85-91 kDa, 58 kDa |
| GenBank蛋白编号 | NM_004579 |
| 基因名称 | MAP4K2 |
| Gene ID (NCBI) | 5871 |
| RRID | AB_10860908 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q12851 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
MAP4K2,also named as GCK and RAB8IP, belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and STE20 subfamily. It enhances MAP3K1 oligomerization, which may relieve amino-terminal mediated MAP3K1 autoinhibition and lead to activation following autophosphorylation. MAP4K2 may play a role in the regulation of vesicle targeting or fusion. This antibody is specific to MAP4K2.






