验证数据展示
产品信息
83561-6-PBS targets MAGI2 in ELISA, WB applications and shows reactivity with rat, human samples.
| 经测试应用 | ELISA, WB Application Description |
| 经测试反应性 | rat, human |
| 免疫原 |
CatNo: Ag18279 Product name: Recombinant human MAGI2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 563-912 aa of BC150277 Sequence: DRPPHSLHSMPTDGQLDGTYPPPVHDDNVSMASSGATQAELMTLTIVKGAQGFGFTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCPIGSETSLIIHRGGFFSPWKTPKPIMDRWENQGSPQTSLSAPAIPQNLPFPPALHRSSFPDSTEAFDPRKPDPYELYEKSRAIYESRRPDYKELDVHLRRMESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASHSLQTSDVVIHRK 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| 别名 | AIP-1, AIP1, AIP 1, ACVRIP1, ACVRINP1 |
| 计算分子量 | 1455 aa, 159 kDa |
| GenBank蛋白编号 | BC150277 |
| 基因名称 | MAGI2 |
| Gene ID (NCBI) | 9863 |
| RRID | AB_3671176 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | Q86UL8 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
MAGI proteins are scaffolding proteins, belonging to the Membrane-Associated Guanylate Kinase Inverted proteins of the MAGUK family. There are three members of the MAGI subfamily, MAGI-1, MAGI-2, and MAGI-3. They are comprised of 6 PDZ domains, 2 WW domains, and 1 GUK domain. They have been proven to mediate the transport and signal transduction of various G protein-coupled receptors (GPCRs) (PMID: 29625175). The antibody is specific to MAGI2.
