验证数据展示
产品信息
60211-1-PBS targets LYN in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IHC, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | LYN fusion protein Ag12723 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog |
别名 | JTK8, LYN, Tyrosine protein kinase Lyn |
计算分子量 | 512 aa, 59 kDa |
观测分子量 | 56 kDa |
GenBank蛋白编号 | BC075002 |
基因名称 | LYN |
Gene ID (NCBI) | 4067 |
RRID | AB_10949077 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P07948 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
LYN, also named as JTK8, p53Lyn and p56Lyn, belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. It is a non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors and plays an important role in the regulation of innate and adaptive immune responses, hematopoiesis, responses to growth factors and cytokines, integrin signaling, but also responses to DNA damage and genotoxic agents. LYN is a component of the mTOR (mammalian target of rapamycin) pathway.