Anti-Human LRP1 (5A6)

LRP1 Monoclonal Antibody for FC
Cat No. 65233-1-Ig

产品说明书

CloneNo. 5A6

宿主/亚型

Mouse / IgG2b

种属反应性

Human

应用

FC

A2MR, Alpha 2 macroglobulin receptor, APOER, Apolipoprotein E receptor, APR, CD91, FLJ16451, IGFBP3R, LRP, LRP 1, LRP1, LRPICD, TGFBR5

缓冲液配方:  PBS and Azide
PBS and Azide
规格价格库存


经过测试的应用

Positive FC detected inU-87 MG cells

推荐稀释比

应用推荐稀释比
Flow Cytometry (FC)FC : 1 ug per 10^6 cells in 100 μl suspension
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

65233-1-Ig targets LRP1 in FC applications and shows reactivity with Human samples.

经测试应用 FC Application Description
经测试反应性 Human
免疫原 Full length native protein (purified) 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)
别名 A2MR, Alpha 2 macroglobulin receptor, APOER, Apolipoprotein E receptor, APR, CD91, FLJ16451, IGFBP3R, LRP, LRP 1, LRP1, LRPICD, TGFBR5
计算分子量 505 kDa
GenBank蛋白编号BC045107
基因名称 LRP1
Gene ID (NCBI) 4035
RRIDAB_3084909
偶联类型 Unconjugated
形式 Liquid
纯化方式Affinity purification
UNIPROT IDQ07954
储存缓冲液 PBS with 0.09% sodium azide, pH 7.3.
储存条件Store at 2-8°C. Stable for one year after shipment.

背景介绍

LRP1 (Prolow-density lipoprotein receptor-related protein 1), also known as A2MR, APOER and CD91, is a type I transmembrane protein that belongs to the LDLR family. LRP1 is synthesized as a transmembrane glycosylated precursor of 600 kDa, and is subsequently cleaved to generate a large 515-kDa N-terminal extracellular subunit and an 85-kDa C-terminal transmembrane subunit, which are noncovalently associated with one another (PMID: 2112085; 8546712). LRP1 is a multifunctional receptor involved in the clearance of a large number of diverse ligands and modulating various cellular processes. LRP1 is implicated in conditions such as atherosclerosis, cancer and neurodegenerative diseases (PMID: 28381441).

实验方案

Product Specific Protocols
FC protocol for LRP1 antibody 65233-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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