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验证数据展示

  • IHC staining of mouse brain using 30142-1-AP (same clone as 30142-1-PBS)

    IHC staining of mouse brain using 30142-1-AP (same clone as 30142-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 30142-1-AP (LPHN1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30142-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 30142-1-AP (same clone as 30142-1-PBS)

    IHC staining of mouse brain using 30142-1-AP (same clone as 30142-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 30142-1-AP (LPHN1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30142-1-PBS in a different storage buffer formulation.

  • IHC staining of rat kidney using 30142-1-AP (same clone as 30142-1-PBS)

    IHC staining of rat kidney using 30142-1-AP (same clone as 30142-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using 30142-1-AP (LPHN1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30142-1-PBS in a different storage buffer formulation.

  • IHC staining of rat kidney using 30142-1-AP (same clone as 30142-1-PBS)

    IHC staining of rat kidney using 30142-1-AP (same clone as 30142-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using 30142-1-AP (LPHN1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30142-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse kidney using 30142-1-AP (same clone as 30142-1-PBS)

    IHC staining of mouse kidney using 30142-1-AP (same clone as 30142-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 30142-1-AP (LPHN1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30142-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse kidney using 30142-1-AP (same clone as 30142-1-PBS)

    IF Staining of mouse kidney using 30142-1-AP (same clone as 30142-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse kidney tissue using LPHN1 antibody (30142-1-AP) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30142-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse kidney using 30142-1-AP (same clone as 30142-1-PBS)

    IF Staining of mouse kidney using 30142-1-AP (same clone as 30142-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse kidney tissue using LPHN1 antibody (30142-1-AP) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30142-1-PBS in a different storage buffer formulation.

LPHN1 Polyclonal antibody, PBS Only

LPHN1 Polyclonal Antibody for IHC, IF-P, Indirect ELISA
Cat No. 30142-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

IHC, IF-P, Indirect ELISA

别名

CIRL-1, CIRL1, CIRL 1, Calcium-independent alpha-latrotoxin receptor 1, Adhesion G protein-coupled receptor L1

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

30142-1-PBS targets LPHN1 in IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 IHC, IF-P, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag31093

Product name: Recombinant human LPHN1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 400-500 aa of NM_001008701

Sequence: DPSAGPATSPPLSTTTTARPTPLTSTASPAATTPLRRAPLTTHPVGAINQLGPDLPPATAPVPSTRRPPAPNLHVSPELFCEPREVRRVQWPATQQGMLVE

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 latrophilin 1
别名 CIRL-1, CIRL1, CIRL 1, Calcium-independent alpha-latrotoxin receptor 1, Adhesion G protein-coupled receptor L1
计算分子量 163 kDa
GenBank蛋白编号NM_001008701
基因名称 LPHN1
Gene ID (NCBI) 22859
RRIDAB_3742328
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDO94910
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Latrophilin-1 (LPHN1) was isolated as the main high-affinity receptor for α-latrotoxin from black widow spider venom, a powerful presynaptic secretagogue (PMID: 30967757). aGPCR latrophilin 1 (ADGRL1/LPHN1) is involved in controlling energy balance and food intake. Although this receptor is present in adipocytes and many neurons, where it is essential for axon growth cone formation and neuronal. It is present in Adipocytes and many neurons, where it is essential for Axon growth cone formation and neuronal function (PMID: 38664368).

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