• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
Use Able AI chat for product recommendations

验证数据展示

  • WB analysis of HeLa using 14236-1-AP (same clone as 14236-1-PBS)

    WB analysis of HeLa using 14236-1-AP (same clone as 14236-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 14236-1-AP (SLC39A6/ZIP6antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14236-1-PBS in a different storage buffer formulation.

  • WB analysis using 14236-1-AP (same clone as 14236-1-PBS)

    WB analysis using 14236-1-AP (same clone as 14236-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14236-1-AP (SLC39A6/ZIP6 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14236-1-PBS in a different storage buffer formulation.

  • IHC staining of human pancreas cancer using 14236-1-AP (same clone as 14236-1-PBS)

    IHC staining of human pancreas cancer using 14236-1-AP (same clone as 14236-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 14236-1-AP (SLC39A6/ZIP6 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14236-1-PBS in a different storage buffer formulation.

  • IHC staining of human pancreas cancer using 14236-1-AP (same clone as 14236-1-PBS)

    IHC staining of human pancreas cancer using 14236-1-AP (same clone as 14236-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 14236-1-AP (SLC39A6/ZIP6 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14236-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

SLC39A6/ZIP6 Polyclonal antibody, PBS Only

SLC39A6/ZIP6 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 14236-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

LIV 1, LIV-1/ZIP6, SLC39A6, ZIP6, Estrogen-regulated protein LIV-1

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

14236-1-PBS targets SLC39A6/ZIP6 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag5478

Product name: Recombinant human SLC39A6 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 101-283 aa of BC039498

Sequence: HLLPHSHASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQKKPENDDDVEIKKQLSKYESQLSTNEEKVDTDDRTEGYLRADSQEPSHFDSQQPAVLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDDLIHHH

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 solute carrier family 39 (zinc transporter), member 6
别名 LIV 1, LIV-1/ZIP6, SLC39A6, ZIP6, Estrogen-regulated protein LIV-1
计算分子量 85 kDa
观测分子量 85-103 kDa, 48 and 32 kDa
GenBank蛋白编号BC039498
基因名称 SLC39A6/ZIP6
Gene ID (NCBI) 25800
RRIDAB_10596924
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ13433
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The zinc transporter LIV-1 (also known as SLC39A6 or ZIP6) was originally identified as an estrogen-induced gene in breast cancer cells. Elevated LIV-1 expression is reportedly related to cancer progression in various types of cancer, including breast, prostate, pancreatic, cervical and liver cancers. While correlation of LIV-1 and prognosis may vary. LIV 1 has 3 isoforms with MW of 85-100 (glycosylation and phosphorylation), 48 and 32 kDa while migrates as different bands in different lysates in SDS-PAGE. Furthermore, it has been reported in the papers that full-length SLC39A6/ZIP6, as the pro-protein, is predicted to be 85 kDa and produces a 103 kDa band, the N-terminal fragment after cleavage is 35 kDa, and the cleaved ZIP6 is 68 kDa (PMID: 23919497, PMID: 26444413).

||
New chat Able
正在加载，请稍候...