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验证数据展示

  • WB analysis of HeLa using 14236-1-AP (same clone as 14236-1-PBS)

    WB analysis of HeLa using 14236-1-AP (same clone as 14236-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 14236-1-AP (LIV-1/ZIP6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14236-1-PBS in a different storage buffer formulation.

  • WB analysis using 14236-1-AP (same clone as 14236-1-PBS)

    WB analysis using 14236-1-AP (same clone as 14236-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14236-1-AP (LIV-1/ZIP6 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14236-1-PBS in a different storage buffer formulation.

  • IHC staining of human pancreas cancer using 14236-1-AP (same clone as 14236-1-PBS)

    IHC staining of human pancreas cancer using 14236-1-AP (same clone as 14236-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 14236-1-AP (LIV-1/ZIP6 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14236-1-PBS in a different storage buffer formulation.

  • IHC staining of human pancreas cancer using 14236-1-AP (same clone as 14236-1-PBS)

    IHC staining of human pancreas cancer using 14236-1-AP (same clone as 14236-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 14236-1-AP (LIV-1/ZIP6 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14236-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

LIV-1/ZIP6 Polyclonal antibody, PBS Only

LIV-1/ZIP6 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 14236-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

LIV 1, SLC39A6, ZIP6, Estrogen-regulated protein LIV-1, LIV1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

14236-1-PBS targets LIV-1/ZIP6 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 LIV-1/ZIP6 fusion protein Ag5478 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 solute carrier family 39 (zinc transporter), member 6
别名 LIV 1, SLC39A6, ZIP6, Estrogen-regulated protein LIV-1, LIV1
计算分子量 85 kDa
观测分子量 85-100 kDa, 48 and 32 kDa
GenBank蛋白编号BC039498
基因名称 SLC39A6/ZIP6
Gene ID (NCBI) 25800
RRIDAB_10596924
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ13433
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The zinc transporter LIV-1 (also known as SLC39A6 or ZIP6) was originally identified as an estrogen-induced gene in breast cancer cells. Elevated LIV-1 expression is reportedly related to cancer progression in various types of cancer, including breast, prostate, pancreatic, cervical and liver cancers. While correlation of LIV-1 and prognosis may vary. LIV 1 has 3 isoforms with MW of 85-100 (glycosylation and phosphorylation), 48 and 32 kDa while migrates as different bands in different lysates in SDS-PAGE.