验证数据展示
产品信息
32267-1-PBS targets LINGO3 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag37289 Product name: Recombinant human LINGO3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 360-530 aa of NM_001101391 Sequence: LLWIVQRRKTLNFDGRLPACATPAEVRGDALRNLPDSVLFEYFVCRKPKIRERRLQRVTATAGEDVRFLCRAEGEPAPTVAWVTPQHRPVTATSAGRARVLPGGTLEIQDARPQDSGTYTCVASNAGGNDTYFATLTVRPEPAANRTPGEAHNETLAALRAPLDLTTILVS 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | leucine rich repeat and Ig domain containing 3 |
| 别名 | LERN2, Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3, Leucine-rich repeat neuronal protein 2, Leucine-rich repeat neuronal protein 6B, LRRN6B |
| 计算分子量 | 64kDa |
| 观测分子量 | 67 kDa |
| GenBank蛋白编号 | NM_001101391 |
| 基因名称 | LINGO3 |
| Gene ID (NCBI) | 645191 |
| RRID | AB_3742558 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | P0C6S8 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
LINGO3 represents a previously unrecognized factor that promotes mucosal wound healing. It partially transduces the repair signals of TFF2, especially through the MAPK signaling cascade, and facilitates epithelial regeneration by preserving the intestinal stem cell microenvironment and maintaining Lgr5 expression (PMID: 33941035).
