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验证数据展示

  • WB analysis of HepG2 using 23307-1-AP (same clone as 23307-1-PBS)

    WB analysis of HepG2 using 23307-1-AP (same clone as 23307-1-PBS)

    HepG2 cells were subjected to SDS PAGE followed by western blot with 23307-1-AP (LGALS3BP antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23307-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 23307-1-AP (same clone as 23307-1-PBS)

    IHC staining of human breast cancer using 23307-1-AP (same clone as 23307-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer slide using 23307-1-AP (LGALS3BP Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 23307-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 23307-1-AP (same clone as 23307-1-PBS)

    IHC staining of human breast cancer using 23307-1-AP (same clone as 23307-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer slide using 23307-1-AP (LGALS3BP Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 23307-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 23307-1-AP (same clone as 23307-1-PBS)

    IF Staining of HepG2 using 23307-1-AP (same clone as 23307-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using LGALS3BP antibody (23307-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 23307-1-PBS in a different storage buffer formulation.

LGALS3BP Polyclonal antibody, PBS Only

LGALS3BP Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 23307-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

LG3BP, Lectin galactoside-binding soluble 3-binding protein, Galectin-3-binding protein, Galectin 3 binding protein, BTBD17B

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

23307-1-PBS targets LGALS3BP in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 LGALS3BP fusion protein Ag19700 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 lectin, galactoside-binding, soluble, 3 binding protein
别名 LG3BP, Lectin galactoside-binding soluble 3-binding protein, Galectin-3-binding protein, Galectin 3 binding protein, BTBD17B
计算分子量 585 aa, 65 kDa
观测分子量 65-70 kDa
GenBank蛋白编号BC002403
基因名称 LGALS3BP
Gene ID (NCBI) 3959
RRIDAB_2879251
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ08380
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-3-binding protein (LGALS3BP, also known as 90K or Mac-2 BP) is a secreted glycoprotein which binds galectin-3, galectin-1, beta1 integrins, collagens and fibronectin (PMID: 8034587; 8024581; 11146440; 9501082). It has been implicated in tumor metastatic processes, as well as in other cell adhesion and immune functions. Levels of LGALS3BP have been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV) (PMID: 7698018). Western analysis suggests that LGALS3BP is found in breast milk, semen, saliva, urine, and tears, in addition to serum (PMID: 8390986 ).