验证数据展示
经过测试的应用
| Positive WB detected in | HeLa cells, SKOV-3 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| WB | See 1 publications below |
产品信息
10113-2-AP targets LDOC1 in WB, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, ELISA Application Description |
| 文献引用应用 | WB |
| 经测试反应性 | human, mouse |
| 文献引用反应性 | human |
| 免疫原 | LDOC1 fusion protein Ag0158 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | leucine zipper, down-regulated in cancer 1 |
| 别名 | LDOC1, Mar7, Mart7, Protein LDOC1 |
| 计算分子量 | 17 kDa |
| 观测分子量 | 17 kDa, 25 kDa |
| GenBank蛋白编号 | BC003104 |
| 基因名称 | LDOC1 |
| Gene ID (NCBI) | 23641 |
| RRID | AB_2135421 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | O95751 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. LDOC1 localizes to the nucleus and is down-regulated in some cancer cell lines. LDOC1 regulates the transcriptional response mediated by the nuclear factor B (NF-kappa B). The gene encoding LDOC1 protein has been proposed as a tumor suppressor gene which may have an important role in the development and/or progression of some cancers.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for LDOC1 antibody 10113-2-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |