验证数据展示
经过测试的应用
| Positive WB detected in | A431 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
19698-1-AP targets LAMC2 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 文献引用应用 | WB, IHC, IF |
| 经测试反应性 | human, mouse, rat |
| 文献引用反应性 | human, mouse, rat |
| 免疫原 | Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | laminin, gamma 2 |
| 别名 | B2T, BM600, CSF, CSF 140 kDa subunit, EBR2, EBR2A, Epiligrin subunit gamma, Kalinin subunit gamma, Ladsin 140 kDa subunit, LAMB2T, LAMC2, Laminin 5 subunit gamma, Laminin B2t chain, Laminin subunit gamma 2, laminin, gamma 2, LAMNB2, Nicein subunit gamma |
| 计算分子量 | 131 kDa |
| 观测分子量 | 140 kDa |
| GenBank蛋白编号 | NM_005562 |
| 基因名称 | LAMC2 |
| Gene ID (NCBI) | 3918 |
| RRID | AB_10644139 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q13753 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
LAMC2, also named as LAMB2T and LAMNB2, is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. LAMC2 binds to cells via a high affinity receptor. Laminin exerts cell-scattering activity toward a wide variety of cells, including epithelial, endothelial, and fibroblastic cells.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for LAMC2 antibody 19698-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
J Proteomics Proteomic analysis reveals the protective effects of emodin on severe acute pancreatitis induced lung injury by inhibiting neutrophil proteases activity. | ||
Mol Med Rep Laminin‑332 mediates proliferation, apoptosis, invasion, migration and epithelial‑to‑mesenchymal transition in pancreatic ductal adenocarcinoma. | ||
Sci Transl Med Connexins orchestrate progression of breast cancer metastasis to the brain by promoting FAK activation | ||
J Transl Med Endothelium-specific deletion of p62 causes organ fibrosis and cardiac dysfunction | ||
iScience Hypoxia promotes histone H3K9 lactylation to enhance LAMC2 transcription in esophageal squamous cell carcinoma | ||
Toxicol Appl Pharmacol The anti-cancer mechanism of Celastrol by targeting JAK2/STAT3 signaling pathway in gastric and ovarian cancer |