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L3MBTL2 Polyclonal antibody

L3MBTL2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat No : 24435-1-AP

Print datasheet

Synonyms

H l(3)mbt l, H l(3)mbt like protein 2, l(3)mbt like 2 (Drosophila), L(3)mbt like protein 2, L3MBT, L3MBTL2

验证数据展示

  • WB analysis using 24435-1-AP

    WB analysis using 24435-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 24435-1-AP (L3MBTL2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inU2OS cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

24435-1-AP targets L3MBTL2 in WB, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA
Tested Reactivity human
Immunogen L3MBTL2 fusion protein Ag19571 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name l(3)mbt-like 2 (Drosophila)
Synonyms H l(3)mbt l, H l(3)mbt like protein 2, l(3)mbt like 2 (Drosophila), L(3)mbt like protein 2, L3MBT, L3MBTL2
Calculated Molecular Weight 705 aa, 79 kDa
Observed Molecular Weight95-100 kDa
GenBank Accession NumberBC017191
Gene Symbol L3MBTL2
Gene ID (NCBI) 83746
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ969R5
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

L3MBTL2 (Lethal (3) malignant brain tumor like 2) is a member of the MBT-domain proteins, which are involved in transcriptional repression and implicated in chromatin compaction. L3MBTL2 was most highly expressed in pachytene spermatocytes within the testis (PMID: 30760872).In addition, mutations in L3MBTL2 are prevalent in various cancers including leukemia, a disease characterized by alterations in multiple DNA repair proteins (PMID: 29581593).

实验方案

Product Specific Protocols
WB protocol for L3MBTL2 antibody 24435-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols