验证数据展示
经过测试的应用
| Positive WB detected in | mouse skin tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
26149-1-AP targets Cytokeratin 71 in WB, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag23536 Product name: Recombinant human KRT71 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 450-523 aa of BC103917 Sequence: PVSISIISSTSGGSGYGFRPSMVSGGYVANSSNCISGVCSVRGGEGRSRGSANDYKDTLGKGSSLSAPSKKTSR 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | keratin 71 |
| 别名 | KRT71, CK 71, CK-71, Cytokeratin-71, hK6irs |
| 观测分子量 | 57 kDa |
| GenBank蛋白编号 | BC103917 |
| 基因名称 | KRT71 |
| Gene ID (NCBI) | 112802 |
| RRID | AB_3085843 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q3SY84 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
KRT71 is a gene that encodes Keratin 71, a type II intermediate filament protein primarily expressed in the inner root sheath (IRS) of hair follicles. As a member of the keratin family, KRT71 plays a critical role in maintaining the structural integrity of hair shafts and follicular tissues. Mutations in this gene have been linked to hereditary hair disorders, including autosomal recessive woolly hair (ARWH) and hypotrichosis, characterized by abnormal hair texture, density, or growth patterns.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for Cytokeratin 71 antibody 26149-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
