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验证数据展示

  • WB analysis of mouse cerebellum using 15505-1-AP (same clone as 15505-1-PBS)

    WB analysis of mouse cerebellum using 15505-1-AP (same clone as 15505-1-PBS)

    mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with 15505-1-AP (KISS1R-Specific antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15505-1-PBS in a different storage buffer formulation.

  • IF Staining of MCF-7 using 15505-1-AP (same clone as 15505-1-PBS)

    IF Staining of MCF-7 using 15505-1-AP (same clone as 15505-1-PBS)

    Immunofluorescent analysis of MCF-7 cells, using KISS1R antibody 15505-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). This data was developed using the same antibody clone with 15505-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse cerebellum using 15505-1-AP (same clone as 15505-1-PBS)

    IHC staining of mouse cerebellum using 15505-1-AP (same clone as 15505-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 15505-1-AP (KISS1R-Specific antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15505-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse cerebellum using 15505-1-AP (same clone as 15505-1-PBS)

    IHC staining of mouse cerebellum using 15505-1-AP (same clone as 15505-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 15505-1-AP (KISS1R-Specific antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15505-1-PBS in a different storage buffer formulation.

KISS1R-Specific Polyclonal antibody, PBS Only

KISS1R-Specific Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 15505-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

15505-1-PBS targets KISS1R-Specific in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 KISS1 receptor
别名
计算分子量 43 kDa
观测分子量75 kDa, 43-45 kDa
GenBank蛋白编号NM_032551
基因名称 KISS1R
Gene ID (NCBI) 84634
RRIDAB_10640578
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ969F8
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

KISS1R is the receptor for metastin (kisspeptin-54, 13, 14, 10), C- terminally amidated peptides of KISS-1. KISS-1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some other carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.

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