验证数据展示
经过测试的应用
Positive WB detected in | A549 cells, LNCaP cells, HeLa cells, HepG2 cells, Jurkat cells, K-562 cells, HSC-T6 cells |
Positive IF/ICC detected in | HepG2 cells |
推荐稀释比
应用 | 推荐稀释比 |
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Western Blot (WB) | WB : 1:5000-1:50000 |
Immunofluorescence (IF)/ICC | IF/ICC : 1:500-1:2000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
68245-1-Ig targets KIAA2013 in WB, IF/ICC, ELISA applications and shows reactivity with human, rat samples.
经测试应用 | WB, IF/ICC, ELISA Application Description |
经测试反应性 | human, rat |
免疫原 | KIAA2013 fusion protein Ag27438 种属同源性预测 |
宿主/亚型 | Mouse / IgG2b |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | KIAA2013 |
别名 | 4G6C4 |
观测分子量 | 65 kDa |
GenBank蛋白编号 | BC035033 |
基因名称 | KIAA2013 |
Gene ID (NCBI) | 90231 |
RRID | AB_3085048 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q8IYS2 |
储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
KIAA2013, also known as Q8IYS2 or MGC33867, is a single-pass transmembrane protein encoded by the KIAA2013 gene in humans. KIAA2013 has been found to play a role in the Endocannabinoid system. This system is made up of cannabinoid receptors 1 and 2 (CB1 and CB2) as well as the various ligands and enzymes that interact. The protein KIAA2013 has been found to be expressed within CB2 expressing cells. Both cannabinoid receptors are labeled as class A G-Protein Coupled Receptors, and CB2 is highly expressed within the human spleen and leukocytes. CB2, and by extension KIAA2013, are therefore targets of interest for therapeutic studies looking into diseases such as inflammatory bowel disease and rheumatoid arthritis(PMID:31616248 34752341).
实验方案
Product Specific Protocols | |
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WB protocol for KIAA2013 antibody 68245-1-Ig | Download protocol |
IF protocol for KIAA2013 antibody 68245-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |