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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 86017-1-RR (same clone as 86017-1-PBS)

    WB analysis using 86017-1-RR (same clone as 86017-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86017-1-RR (KDM5C antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86017-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86017-1-RR

    Affinity and Kinetic Characterization of 86017-1-RR

    Biolayer interferometry (BLl) kinetic assays of 86017-1-RR against Human KDM5C were performed. The affinity constant is 0.148 nM.

KDM5C Recombinant antibody, PBS Only

KDM5C Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 86017-1-PBS

产品说明书

CloneNo. 250484C10

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, Indirect ELISA

别名

[histone H3]-trimethyl-L-lysine(4) demethylase 5C, DXS1272E, EC:1.14.11.67, JARID1C, Jumonji/ARID domain-containing protein 1C

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

86017-1-PBS targets KDM5C in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 KDM5C fusion protein Ag5791 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 lysine (K)-specific demethylase 5C
别名 [histone H3]-trimethyl-L-lysine(4) demethylase 5C, DXS1272E, EC:1.14.11.67, JARID1C, Jumonji/ARID domain-containing protein 1C
计算分子量 176 kDa
观测分子量171-180 kDa
GenBank蛋白编号BC054499
基因名称 KDM5C
Gene ID (NCBI) 8242
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP41229
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

KDM5C belongs to the ARID protein family that harbors conserved DNA-binding motifs and acts as a histone H3 lysine 4 demethylase, suggesting a potential role in epigenetic regulation during development, cell differentiation (PMID:21575681). KDM5C protein is homologous to three other proteins of the human JARID1 family (JARID1A, JARID1B and JARID1C). This family shares several evolutionarily conserved domains, including the catalytic JmjC domain, JmjN domain, Arid/Bright domain, C5HC2 zinc-finger domain and two plant homeodomains (PHD), a motif that binds methyl-lysine residues (PMID:17320160,17320161).