KDM4B Polyclonal antibody

KDM4B Polyclonal Antibody for ELISA
Cat No. 20038-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

ELISA

JHDM3B, JMJD2B, KDM4B, KIAA0876, lysine (K) demethylase 4B, Lysine specific demethylase 4B

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
规格: 

-/ -


产品信息

20038-1-AP targets KDM4B in ELISA applications and shows reactivity with human samples.

经测试应用 ELISA Application Description
经测试反应性 human
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 lysine (K)-specific demethylase 4B
别名 JHDM3B, JMJD2B, KDM4B, KIAA0876, lysine (K) demethylase 4B, Lysine specific demethylase 4B
计算分子量 122 kDa
GenBank蛋白编号NM_015015
基因名称 KDM4B
Gene ID (NCBI) 23030
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO94953
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

KDM4B, also named as JHDM3B, JMJD2B and KIAA0876, belongs to the JHDM3 histone demethylase family. KDM4B is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. It does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. KDM4B is able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. The antibody recognizes near the C-term of KDM4B and has no cross reaction to KDM4A.

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