验证数据展示
经过测试的应用
| Positive WB detected in | SH-SY5Y cells, mouse brain tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
12684-1-AP targets KCNV1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag3376 Product name: Recombinant human KCNV1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-210 aa of BC028739 Sequence: MPSSGRALLDSPLDSGSLTSLGSSVFCSEGEGEPLALGDCFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAAR 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | potassium channel, subfamily V, member 1 |
| 别名 | HNKA, KCNB3, KV2.3, KV8.1, Potassium voltage-gated channel subfamily V member 1 |
| 计算分子量 | 500 aa, 56 kDa |
| 观测分子量 | 70 kDa |
| GenBank蛋白编号 | BC028739 |
| 基因名称 | KCNV1 |
| Gene ID (NCBI) | 27012 |
| RRID | AB_2877874 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q6PIU1 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Potassium voltage-gated channel subfamily V member 1 (KCNV1, also known as Kv8.1) is a voltage-gated potassium channel that plays a role in the repolarization phase of the action potential (PMID: 39003683). It regulates neuronal excitability and is essential for maintaining normal electrical signaling in the nervous system (PMID: 38911266). The function of KCNV1 may also include inhibiting specific types of outwardly rectifying potassium channels (PMID: 8670833).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for KCNV1 antibody 12684-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
