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Host
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Species Reactivity
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验证数据展示

  • WB analysis of human blood using 60276-1-Ig (same clone as 60276-1-PBS)

    WB analysis of human blood using 60276-1-Ig (same clone as 60276-1-PBS)

    human blood were subjected to SDS PAGE followed by western blot with 60276-1-Ig (KCNN4 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60276-1-PBS in a different storage buffer formulation.

KCNN4 Monoclonal antibody, PBS Only

KCNN4 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 60276-1-PBS

产品说明书

CloneNo. 2A6G5

宿主/亚型

Mouse / IgG2a

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

hIKCa1, hKCa4, hSK4, IK1, IKCA1, KCa3.1, KCA4, KCNN4, Putative Gardos channel, SK4, SKCa 4, SKCa4

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

60276-1-PBS targets KCNN4 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag19774

Product name: Recombinant human KCNN4 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 128-427 aa of BC015337

Sequence: VQDLGAPLTSPQPWPGFLGQGEALLSLAMLLRLYLVPRAVLLRSGVLLNASYRSIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDIQYTKEMKESAARVLQEAWMFYKHTRRKESHAARRHQRKLLAAINAFRQVRLKHRKLREQVNSMVDISKMHMILYDLQQNLSSSHRALEKQIDTLAGKLDALTELLSTALGPRQLPEPSQQSK

种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
别名 hIKCa1, hKCa4, hSK4, IK1, IKCA1, KCa3.1, KCA4, KCNN4, Putative Gardos channel, SK4, SKCa 4, SKCa4
计算分子量 427 aa, 48 kDa
观测分子量 48 kDa
GenBank蛋白编号BC015337
基因名称 KCNN4
Gene ID (NCBI) 3783
RRIDAB_2881395
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDO15554
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The intermediate conductance calcium-activated potassium channel KCNN4, also known as KCa3.1, IK1, or SK4, is a member of the potassium channel KCNN family. KCNN4 is expressed in T cells, mast cells, macrophages, erythrocytes, vascular smooth muscle cells, airway smooth muscle cells, intestinal and airway epithelial cells (PMID: 19681865; 21493782). Functionally, KCNN4 plays a key role in calcium-dependent cell functions, such as proliferation, activation, and migration, in a broad range of cell types (PMID: 21493782).