×
Use Able AI chat for product recommendations

验证数据展示

  • WB analysis using 22158-1-AP (same clone as 22158-1-PBS)

    WB analysis using 22158-1-AP (same clone as 22158-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 22158-1-AP (KCNMA1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22158-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse cerebellum using 22158-1-AP (same clone as 22158-1-PBS)

    IHC staining of mouse cerebellum using 22158-1-AP (same clone as 22158-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 22158-1-AP (KCNMA1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22158-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse brain using 22158-1-AP (same clone as 22158-1-PBS)

    IF Staining of mouse brain using 22158-1-AP (same clone as 22158-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse brain tissue using KCNMA1 antibody (22158-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22158-1-PBS in a different storage buffer formulation.

KCNMA1 Polyclonal antibody, PBS Only

KCNMA1 Polyclonal Antibody for WB, IHC, IF-P, Indirect ELISA
Cat No. 22158-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF-P, Indirect ELISA

别名

BK channel, BKCA alpha, BKTM, hSlo, K(VCA)alpha

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

22158-1-PBS targets KCNMA1 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF-P, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag17802

Product name: Recombinant human KCNMA1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 829-1178 aa of BC137115

Sequence: KREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRQNRPKSRESRDKQKYVQEERL

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 potassium large conductance calcium-activated channel, subfamily M, alpha member 1
别名 BK channel, BKCA alpha, BKTM, hSlo, K(VCA)alpha
计算分子量 1236 aa, 138 kDa
观测分子量~130 kDa
GenBank蛋白编号BC137115
基因名称 KCNMA1
Gene ID (NCBI) 3778
RRIDAB_3669389
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ12791
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Calcium-activated potassium channel subunit alpha-1 also known as large conductance calcium-activated potassium channel, subfamily M, alpha member 1 (KCa1.1), or BK channel alpha subunit, is a voltage-gated potassium channel encoded by the KCNMA1 gene and characterized by their large conductance of potassium ions (K+) through cell membranes. KCNMA1 is widely distributed in human cell membranes, especially in muscle cells and neurons. They regulate the excitability of cells through sensitivity to calcium ions (Ca²⁺) and voltage, thereby affecting key physiological processes such as muscle contraction and nerve signal transduction.

||
New chat

Able™

正在加载，请稍候...