验证数据展示
经过测试的应用
| Positive WB detected in | HeLa cells, mouse liver tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
17912-1-AP targets KCNH5 in WB, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 | KCNH5 fusion protein Ag12312 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | potassium voltage-gated channel, subfamily H (eag-related), member 5 |
| 别名 | EAG2, H EAG2, hEAG2, KCNH5, Kv10.2 |
| 计算分子量 | 988 aa, 112 kDa |
| 观测分子量 | 69-71 kDa |
| GenBank蛋白编号 | BC073979 |
| 基因名称 | KCNH5 |
| Gene ID (NCBI) | 27133 |
| RRID | AB_3085546 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q8NCM2 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Potassium voltage-gated channel subfamily H member 5 (KCNH5), also known as Ether-a-go-go potassium channel 2 (hEAG2) belongs to mammalian potassium channel subfamily and is upregulated in a subset of Medulloblastoma (MB). KCNH5 protein is confined intracellularly during interphase but is enriched in the plasma membrane during late G2 phase and mitosis (PMID: 22855790, 26258683).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for KCNH5 antibody 17912-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |