CXCR2 Polyclonal antibody

CXCR2 Polyclonal Antibody for IHC, ELISA
Cat No. 19538-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

IHC, ELISA

Cxcr2-Specific, CXCR-2, CXC-R2, C-X-C chemokine receptor type 2, Cmkar2

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive IHC detected inmouse spleen tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

IHCSee 1 publications below

产品信息

19538-1-AP targets CXCR2 in IHC, ELISA applications and shows reactivity with mouse samples.

经测试应用 IHC, ELISA Application Description
文献引用应用IHC
经测试反应性 mouse
文献引用反应性mouse
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 interleukin 8 receptor, beta
别名 Cxcr2-Specific, CXCR-2, CXC-R2, C-X-C chemokine receptor type 2, Cmkar2
计算分子量 41 kDa
GenBank蛋白编号NM_009909
基因名称 Cxcr2
Gene ID (NCBI) 12765
RRIDAB_2878587
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP35343
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CXCR2, also named as Cmkar2, Gpcr16, Il8rb or CD182, belongs to the G-protein coupled receptor 1 family. CXCR2 is a receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. CXCR2 binds to IL-8 with high affinity. CXCR2 also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. This antibody is specific to mouse CXCR2.

实验方案

Product Specific Protocols
IHC protocol for CXCR2 antibody 19538-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseIHC

Adv Sci (Weinh)

Tumor Microenvironment Responsive CD8+ T Cells and Myeloid-Derived Suppressor Cells to Trigger CD73 Inhibitor AB680-Based Synergistic Therapy for Pancreatic Cancer

Authors - Qiangda Chen
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