验证数据展示
产品信息
66312-1-Ig targets Il17a in ELISA applications and shows reactivity with human samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | Il17a fusion protein Ag24087 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG2b |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | interleukin 17A |
| 别名 | Ctla 8, Ctla8, Il17, Il17a, interleukin 17A |
| 计算分子量 | 17 kDa |
| GenBank蛋白编号 | NM-010552 |
| 基因名称 | Il17a |
| Gene ID (NCBI) | 16171 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q62386 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Il17a is a pro-inflammatory cytokine as a member of the interleukin-17 family. It plays a central role in host defense against diverse pathogens. It is produced by activated T-cells and certain cell types of innate immune system. The active protein functions as either a homodimer with other interleukin-17 family members and signals through the interleukin-17 receptor to induce inflammatory cytokine production. Aberrant expression of this gene is associated with autoinflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.