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验证数据展示

  • FC experiment of Transfected HEK-293T using 98407-3-RR (same clone as 98407-3-PBS)

    FC experiment of Transfected HEK-293T using 98407-3-RR (same clone as 98407-3-PBS)

    1x10^6 HEK-293T cells (left) and IL-13RA2-transfected HEK-293T cells (right) were surface stained with 0.25 ug Anti-Mouse IL-13RA2 Rabbit RecAb (98407-3-RR, Clone: 242742C4) and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98407-3-PBS in a different storage buffer formulation.

  • FC experiment of Transfected HEK-293T using 98407-3-RR (same clone as 98407-3-PBS)

    FC experiment of Transfected HEK-293T using 98407-3-RR (same clone as 98407-3-PBS)

    1x10^6 HEK-293T cells (left) and IL-13RA2-transfected HEK-293T cells (right) were surface stained with 0.25 ug Anti-Mouse IL-13RA2 Rabbit RecAb (98407-3-RR, Clone: 242742C4) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-2-RR, Clone: 240953A11) (blue), and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98407-3-PBS in a different storage buffer formulation.

  • Sandwich ELISA standard curve of MP02013-3

    Sandwich ELISA standard curve of MP02013-3

    Sandwich ELISA standard curve of MP02013-3, Mouse IL-13RA2 Recombinant Matched Antibody Pair - PBS only. 98407-3-PBS was coated to a plate as the capture antibody and incubated with serial dilutions of standard Eg3118. 85631-5-PBS was HRP conjugated as the detection antibody. Range: 0.156-10 ng/mL.

  • Sample test of MP02013-3

    Sample test of MP02013-3

    The mean IL-13RA2 concentration was determined to be 1.81 ng/mL in mouse spleen tissue homogenates extract based on a 2.30 mg/mL extract load.

  • Sample test of MP02013-3

    Sample test of MP02013-3

    Serum of eight mice was measured. The IL-13RA2 concentration of detected samples was determined to be 6.65 ng/mL with a range of 5.21-8.88 ng/mL.

Anti-Mouse IL-13RA2 Rabbit Recombinant Antibody, PBS Only (Capture)

IL-13RA2 Recombinant Antibody for FC, Sandwich ELISA, Indirect ELISA, Sample test
Cat No. 98407-3-PBS

产品说明书

CloneNo. 242742C4

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC, Sandwich ELISA, Indirect ELISA, Sample test

别名

CD213a2, IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, Il13ra2, IL-13R-alpha-2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98407-3-PBS targets IL-13RA2 in FC, Sandwich ELISA, Indirect ELISA, Sample test applications and shows reactivity with mouse samples.

经测试应用 FC, Sandwich ELISA, Indirect ELISA, Sample test Application Description
经测试反应性 mouse
免疫原 IL-13RA2 fusion protein Eg3118 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 interleukin 13 receptor, alpha 2
别名 CD213a2, IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, Il13ra2, IL-13R-alpha-2
计算分子量44 kDa
GenBank蛋白编号NM_008356.4
基因名称 Il13ra2
Gene ID (NCBI) 16165
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDO88786-1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IL-13RA2, also named as IL-13R and CD213a2, belongs to the type I cytokine receptor family. It binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4). IL-13RA2 lacks the cytoplasmic domain for signaling, indicating that it acts as a decoy receptor. IL-13RA2 gene polymorphisms have been associated with systemic sclerosis (PMID: 16981293). Overexpression of IL-13RA2 gene has been reported in several types of cancer, including melanoma, lung cancer, and brain tumor, which makes it a potential immunotherapeutic target (PMID: 19895199; 24970476; 24021875).