Mouse IL-10 Recombinant antibody, PBS Only (Detector)

IL-10 Uni-rAbTM Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA
Cat No. 82191-3-PBS

产品说明书

CloneNo. 240430G12

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

WB, Cytometric bead array, Indirect ELISA

Il10, IL-10,IL10, 240430G12, CSIF, Il 10

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

82191-3-PBS targets IL-10 as part of a matched antibody pair:

MP00507-2: 82191-4-PBS capture and 82191-3-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 WB, Cytometric bead array, Indirect ELISA Application Description
经测试反应性 mouse
免疫原 IL-10 fusion protein Eg0026 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 interleukin 10
别名 Il10, IL-10,IL10, 240430G12, CSIF, Il 10
计算分子量 21 kDa
观测分子量20 kDa
GenBank蛋白编号NM_010548
基因名称 Il10
Gene ID (NCBI) 16153
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP18893
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IL-10 is an anti-inflammatory cytokine, produced by T helper (Th) cells, macrophages, monocytes, and B cells, that plays a crucial role in preventing inflammatory and autoimmune pathologies. It downregulates the expression of Th1 cytokines, MHC class II antigens, and co-stimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-κB activity, and is involved in the regulation of the JAK-STAT signaling pathway. IL-10, along with its receptors, describes an important role in pathogenesis of various diseases, including infectious, inflammatory, autoimmune diseases. IL-10 mutations are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

Loading...