Mouse IL-10 Recombinant antibody, PBS Only

IL-10 Uni-rAbTM Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA
Cat No. 82191-3-PBS

产品说明书

CloneNo. 240430G12

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

WB, Cytometric bead array, Indirect ELISA

Il10, IL-10,IL10, 240430G12, CSIF, Il 10

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存


产品信息

82191-3-PBS targets IL-10 in WB, Cytometric bead array, Indirect ELISA applications and shows reactivity with mouse samples.

经测试应用 WB, Cytometric bead array, Indirect ELISA Application Description
经测试反应性 mouse
免疫原 IL-10 fusion protein Eg0026 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 interleukin 10
别名 Il10, IL-10,IL10, 240430G12, CSIF, Il 10
计算分子量 21 kDa
观测分子量20 kDa
GenBank蛋白编号NM_010548
基因名称 Il10
Gene ID (NCBI) 16153
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP18893
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IL-10 is an anti-inflammatory cytokine, produced by T helper (Th) cells, macrophages, monocytes, and B cells, that plays a crucial role in preventing inflammatory and autoimmune pathologies. It downregulates the expression of Th1 cytokines, MHC class II antigens, and co-stimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-κB activity, and is involved in the regulation of the JAK-STAT signaling pathway. IL-10, along with its receptors, describes an important role in pathogenesis of various diseases, including infectious, inflammatory, autoimmune diseases. IL-10 mutations are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

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