验证数据展示
经过测试的应用
| Positive WB detected in | human liver tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
16667-1-AP targets IYD in WB, IF, IHC, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 文献引用应用 | WB, IF, IHC |
| 经测试反应性 | human |
| 文献引用反应性 | human, mouse |
| 免疫原 |
CatNo: Ag10146 Product name: Recombinant human IYD protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 33-289 aa of BC056253 Sequence: EPRTRAEARPWVDEDLKDSSDLHQAEEDADEWQESEENVEHIPFSHNHYPEKEMVKRSQEFYELLNKRRSVRFISNEQVPMEVIDNVIRTAGTAPSGAHTEPWTFVVVKDPDVKHKIRKIIEEEEEINYMKRMGHRWVTDLKKLRTNWIKEYLDTAPILILIFKQVHGFAANGKKKVHYYNEISVSIACGILLAALQNAGLVTVTTTPLNCGPRLRVLLGRPAHEKLPMLLPVGYPSKEATVPDLKRKPLDQIMVTV 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | iodotyrosine deiodinase |
| 别名 | C6orf71, DEHAL1, Iodotyrosine dehalogenase 1, iodotyrosine deiodinase, IYD, IYD 1 |
| 计算分子量 | 289 aa, 33 kDa |
| 观测分子量 | 33 kDa |
| GenBank蛋白编号 | BC056253 |
| 基因名称 | IYD |
| Gene ID (NCBI) | 389434 |
| RRID | AB_1851260 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q6PHW0 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
IYD(Iodotyrosine dehalogenase 1) is also named as C6orf71, DEHAL1 and belongs to the nitroreductase family. It is a transmembrane protein that deiodinates mono-and di-iodotyrosines (MIT, DIT) and recycles iodine, a scarce element in the environment, for the efficient synthesis of thyroid hormone. This protein has 6 isoforms produced by alternative splicing.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for IYD antibody 16667-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Toxicology Structure-activity relationships of 44 halogenated compounds for iodotyrosine deiodinase-inhibitory activity. | ||
Cells Agonist Antibody Converts Stem Cells into Migrating Brown Adipocyte-Like Cells in Heart. | ||
Breast Cancer Res Treat LncRNA HOTAIR as a ceRNA is related to breast cancer risk and prognosis | ||
Cell Tissue Res The role of vitamin D receptor in predentin mineralization and dental repair after injury |