验证数据展示
产品信息
88074-2-PBS targets ITPRIP in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Eg5612 Product name: Recombinant human ITPRIP protein Source: mammalian cells-derived, V37 Tag: C-rFc Domain: 16-83 aa of NM_001272012.2 Sequence: IINHPLLFPRENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQNETR 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | inositol 1,4,5-triphosphate receptor interacting protein |
| 别名 | bA127L20, DANGER, Inositol 1,4,5-trisphosphate receptor-interacting protein, KIAA1754, Protein DANGER |
| 计算分子量 | 62 kDa |
| 观测分子量 | 62 kDa |
| GenBank蛋白编号 | NM_001272012.2 |
| 基因名称 | ITPRIP |
| Gene ID (NCBI) | 85450 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q8IWB1 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ITPRIP (inositol 1,4,5-trisphosphate receptor interacting protein) is a key regulatory protein that binds to IP3 receptors to modulate endoplasmic reticulum calcium release and intracellular calcium homeostasis. It is widely expressed in human tissues with high abundance in the central nervous system. ITPRIP participates in neurodevelopment, cell apoptosis, innate immunity and tumor progression. Its abnormal expression is closely linked to glioma malignancy, neurodevelopmental disorders and immune dysfunction, serving as an essential molecule in physiological regulation and disease pathogenesis. (PMID: 29899107)
