×
Use Able AI chat for product recommendations

验证数据展示

  • IHC staining of human breast cancer using 14267-1-AP (same clone as 14267-1-PBS)

    IHC staining of human breast cancer using 14267-1-AP (same clone as 14267-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 14267-1-AP (ITPKC antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14267-1-PBS in a different storage buffer formulation.

  • WB analysis using 14267-1-AP (same clone as 14267-1-PBS)

    WB analysis using 14267-1-AP (same clone as 14267-1-PBS)

    MDA-MB-453s cells were subjected to SDS PAGE followed by western blot with 14267-1-AP (ITPKC antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14267-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 14267-1-AP (same clone as 14267-1-PBS)

    IF Staining of HepG2 using 14267-1-AP (same clone as 14267-1-PBS)

    Immunofluorescent analysis of HepG2 cells, using ITPKC antibody 14267-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye). This data was developed using the same antibody clone with 14267-1-PBS in a different storage buffer formulation.

  • IP experiment of HepG2 using 14267-1-AP (same clone as 14267-1-PBS)

    IP experiment of HepG2 using 14267-1-AP (same clone as 14267-1-PBS)

    IP result of anti-ITPKC (IP:14267-1-AP, 4ug; Detection:14267-1-AP 1:400) with HepG2 cells lysate 1600ug. This data was developed using the same antibody clone with 14267-1-PBS in a different storage buffer formulation.

ITPKC Polyclonal antibody, PBS Only

ITPKC Polyclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA
Cat No. 14267-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, IF/ICC, IP, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

14267-1-PBS targets ITPKC in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF/ICC, IP, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag5583

Product name: Recombinant human ITPKC protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-358 aa of BC060788

Sequence: MRRCPCRGSLNEAEAGALPAAARMGLEAPRGGRRRQPGQQRPGPGAGAPAGRPEGGGPWARTEGSSLHSEPERAGLGPAPGTESPQAEFWTDGQTEPAAAGLGVETERPKQKTEPDRSSLRTHLEWSWSELETTCLWTETGTDGLWTDPHRSDLQFQPEEASPWTQPGVHGPWTELETHGSQTQPERVKSWADNLWTHQNSSSLQTHPEGACPSKEPSADGSWKELYTDGSRTQQDIEGPWTEPYTDGSQKKQDTEAARKQPGTGGFQIQQDTDGSWTQPSTDGSQTAPGTDCLLGEPEDGPLEEPEPGELLTHLYSHLKCSPLCPVPRLIITPETPEPEAQPVGPPSRVEGGSGGFS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 inositol 1,4,5-trisphosphate 3-kinase C
别名
计算分子量 75 kDa
观测分子量 100-105 kDa
GenBank蛋白编号BC060788
基因名称 ITPKC
Gene ID (NCBI) 80271
RRIDAB_2280728
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ96DU7
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ITPKC(Inositol-trisphosphate 3-kinase C) is also named as IP3KC and belongs to the inositol phosphokinase (IPK) family. It can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate and is relatively weakly activated by the calcium-calmodulin complex. ITPKC also acts as a negative regulator of T-cell activation through the Ca(2+)/NFAT signaling pathway, and the C allele may contribute to immune hyperreactivity in Kawasaki disease(PMID:17160344).

||
New chat

Able™

正在加载，请稍候...