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验证数据展示

  • WB analysis using 12193-1-AP

    WB analysis using 12193-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 12193-1-AP (ITM2B antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

  • WB analysis using 12193-1-AP

    WB analysis using 12193-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 12193-1-AP (ITM2B antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

ITM2B Polyclonal antibody

ITM2B Polyclonal Antibody for WB, ELISA
Cat No. 12193-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

别名

ABRI, Bri, BRI2, BRI2 intracellular domain, BRI2, membrane form

缓冲液配方:  PBS, Azide, Glycerol
PBS, Azide, Glycerol
偶联物:  Unconjugated
Unconjugated
规格价格库存

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经过测试的应用

Positive WB detected inU-251 cells, fetal human brain tissue, U-251 cells unboiled

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

12193-1-AP targets ITM2B in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag2831

Product name: Recombinant human ITM2B protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-266 aa of BC016148

Sequence: MVKVTFNSALAQKETKKDEPKSGEEALIIPPDAVAVDCKDPDDVVPVGQRRAWCWCMCFGLAFMLAGVILGGAYLYKYFALQPDDVYYCGIKYIKDDVILNEPSADAPAALYQTIEENIKIFEEEEVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPRNLLELLINIKAGTYLPQSYLIHEHMVITDRIENIDHLGFFIYRLCHDKETYKLQRRETIKGIQKREASNCFAIRHFENKFAVETLICS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 integral membrane protein 2B
别名 ABRI, Bri, BRI2, BRI2 intracellular domain, BRI2, membrane form
计算分子量 266 aa, 30 kDa
观测分子量 40 kDa
GenBank蛋白编号BC016148
基因名称 ITM2B
Gene ID (NCBI) 9445
RRIDAB_3669134
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9Y287
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

ITM2B plays a regulatory role in the processing of the amyloid-beta A4 precursor protein (APP) and acts as an inhibitor of the amyloid-beta peptide aggregation and fibrils deposition. It plays a role in the induction of neurite outgrowth and functions as a protease inhibitor by blocking access of secretases to APP cleavage sites.

实验方案

Product Specific Protocols
WB protocol for ITM2B antibody 12193-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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