验证数据展示
经过测试的应用
| Positive WB detected in | HL-60 cells, MOLT-4 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
32836-1-AP targets ITFG2 in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag36829 Product name: Recombinant human ITFG2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 210-362 aa of BC006552 Sequence: LLCTWKKDTGSPPASEGPTDGSRETPAARDVVLHQTSGRIHNKNVSTHLIGNIKQGHGTESSGSGLFALCTLDGTLKLMEEMEEADKLLWSVQVDHQLFALEKLDVTGNGHEEVVACAWDGQTYIIDHNRTVVRFQVDENIRAFCAGLYACKE 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | integrin alpha FG-GAP repeat containing 2 |
| 别名 | Integrin-alpha FG-GAP repeat-containing protein 2, KICSTOR complex protein ITFG2, MDS028 |
| 计算分子量 | 49 kDa |
| 观测分子量 | 52 kDa |
| GenBank蛋白编号 | BC006552 |
| 基因名称 | ITFG2 |
| Gene ID (NCBI) | 55846 |
| RRID | AB_3742757 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q969R8 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Integrin-alpha FG-GAP repeat-containing protein 2 (ITFG2) is an immune-modulatory intracellular protein that modulates the fate of B cells and negatively regulates mTORC1 signaling (PMID: 23997217; 28199306). ITFG2 is highly expressed in the heart, which may be a novel strategy for the clinical management of myocardial infarction (PMID: 38848780).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for ITFG2 antibody 32836-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
