IRF9 Recombinant antibody, PBS Only

IRF9 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 85160-2-PBS

产品说明书

CloneNo. 242772F12

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

242772F12, IFN-alpha-responsive transcription factor subunit, Interferon-stimulated gene factor 3 gamma, IRF 9, IRF-9

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存


Planning an IHC experiment? We recommend our IHCeasy IRF9 Ready-To-Use IHC Kit. IRF9 primary antibody included.

产品信息

85160-2-PBS targets IRF9 in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 IRF9 fusion protein Ag5365 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 IRF 9
别名 242772F12, IFN-alpha-responsive transcription factor subunit, Interferon-stimulated gene factor 3 gamma, IRF 9, IRF-9
计算分子量 393 aa, 44 kDa
观测分子量 44-48 kDa
GenBank蛋白编号BC035716
基因名称 IRF9
Gene ID (NCBI) 10379
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ00978
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IRF9 also named ISGF3 is a transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of IFN stimulated genes, which drive the cell in an antiviral state.

Loading...