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INTS3 Polyclonal antibody
INTS3 Polyclonal Antibody for IP, WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
IP, WB, ELISA and More (1)
Conjugate
Unconjugated
验证数据展示
经过测试的应用
| Positive WB detected in | HEK-293 cells, HeLa cells |
| Positive IP detected in | HEK-293 cells |
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| WB | See 9 publications below |
| ChIP | See 2 publications below |
产品信息
16620-1-AP targets INTS3 in WB, IP, chIP, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Applications | IP, WB, ELISA |
| Cited Applications | WB, ChIP |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse |
| Immunogen | INTS3 fusion protein Ag9917 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | integrator complex subunit 3 |
| Synonyms | C1orf193, C1orf60, INT3, integrator complex subunit 3, INTS3, Sensor of ssDNA subunit A, SOSS A, SOSS complex subunit A, SOSS-A |
| Calculated Molecular Weight | 118 kDa |
| Observed Molecular Weight | 118 kDa |
| GenBank Accession Number | BC025254 |
| Gene Symbol | INTS3 |
| Gene ID (NCBI) | 65123 |
| RRID | AB_2127274 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q68E01 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for INTS3 antibody 16620-1-AP | Download protocol |
| IP protocol for INTS3 antibody 16620-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Science Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase. | ||
Cell The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer. | ||
Mol Cell PGC-1α senses the CBC of pre-mRNA to dictate the fate of promoter-proximally paused RNAPII | ||
Mol Cell Integrator Recruits Protein Phosphatase 2A to Prevent Pause Release and Facilitate Transcription Termination. | ||
Mol Cell Deregulated Expression of Mammalian lncRNA through Loss of SPT6 Induces R-Loop Formation, Replication Stress, and Cellular Senescence. | ||
Nat Commun INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex |