验证数据展示
产品信息
86142-1-PBS targets ILT-3/LILRB4 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | ILT-3/LILRB4 fusion protein Eg1743 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 |
别名 | LILRB4, B4, CD85 antigen-like family member K, CD85k, ILT3 |
计算分子量 | 49kDa |
观测分子量 | 49 kDa |
GenBank蛋白编号 | AAH26309.1 |
基因名称 | LILRB4 |
Gene ID (NCBI) | 11006 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q8NHJ6 |
储存缓冲液 | PBS only, pH 7.3. |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
LILRB4 is an inhibitory receptor in the LILR family mainly expressed on normal and malignant human cells of myeloid origin. LILRB4 is activated and subsequently recruits adaptors to cytoplasmic immunoreceptor tyrosine inhibitory motifs to initiate different signaling cascades, thus playing an important role in physiological and pathological conditions, including autoimmune diseases, microbial infections, and cancers.