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- KD/KO Validated
IL-32 Polyclonal antibody
IL-32 Polyclonal Antibody for IHC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human and More (1)
Applications
IHC, ELISA and More (2)
Conjugate
Unconjugated
验证数据展示
经过测试的应用
| Positive IHC detected in | human lung cancer tissue, human colon cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
推荐稀释比
| Application | Dilution |
|---|---|
| Immunohistochemistry (IHC) | IHC : 1:200-1:800 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
11079-1-AP targets IL-32 in WB, IF, IHC, ELISA applications and shows reactivity with human samples.
| Tested Applications | IHC, ELISA |
| Cited Applications | WB, IF, IHC, ELISA |
| Tested Reactivity | human |
| Cited Reactivity | human, mouse |
| Immunogen | IL-32 fusion protein Ag1484 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | interleukin 32 |
| Synonyms | IL 32, IL 32alpha, IL 32beta, IL 32delta, IL 32gamma, IL32, IL-32, interleukin 32, Natural killer cells protein 4, NK4, TAIF, TAIFa, TAIFb, TAIFc, TAIFd |
| Calculated Molecular Weight | 27 kDa |
| GenBank Accession Number | BC009401 |
| Gene Symbol | IL32 |
| Gene ID (NCBI) | 9235 |
| RRID | AB_2877745 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P24001 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Interleukin 32 (IL32) is a member of the cytokine family. IL32 contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. IL32 is a predominantly intracellular proinflammatory cytokine produced by epithelial cells, monocytes, T-lymphocytes and natural killer cells, and is involved in inflammation and cancer development. IL32 is able to induce the release a variety of pro-inflammatory cytokines such as IL8, tumor necrosis factor-α (TNFα) and IL6. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2.
实验方案
| Product Specific Protocols | |
|---|---|
| IHC protocol for IL-32 antibody 11079-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
J Cell Mol Med MicroRNA-29b-3p suppresses oral squamous cell carcinoma cell migration and invasion via IL32/AKT signalling pathway. | ||
J Hepatocell Carcinoma Identification and Validation of Novel Biomarkers for Hepatocellular Carcinoma, Liver Fibrosis/Cirrhosis and Chronic Hepatitis B via Transcriptome Sequencing Technology. | ||
Front Pharmacol Targeting TIGIT Inhibits Bladder Cancer Metastasis Through Suppressing IL-32. | ||
Oncol Lett Interleukin-32 regulates downstream molecules and promotes the invasion of pancreatic cancer cells.
| ||
Oncol Lett Establishment of highly invasive pancreatic cancer cell lines and the expression of IL-32. | ||
Biomed Res Int IL-32 Promotes the Radiosensitivity of Esophageal Squamous Cell Carcinoma Cell through STAT3 Pathway. |
