验证数据展示
经过测试的应用
| Positive WB detected in | human plasma tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| KD/KO | See 2 publications below |
| WB | See 7 publications below |
| IHC | See 3 publications below |
产品信息
55169-1-AP targets IL-11 in WB, IHC, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 文献引用应用 | WB, IHC |
| 经测试反应性 | human |
| 文献引用反应性 | human, mouse, monkey |
| 免疫原 | Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | interleukin 11 |
| 别名 | IL11, Adipogenesis inhibitory factor, AGIF, IL 11, interleukin 11 |
| 计算分子量 | 21 kDa |
| 观测分子量 | 25 kDa |
| GenBank蛋白编号 | NM_000641 |
| 基因名称 | IL-11 |
| Gene ID (NCBI) | 3589 |
| RRID | AB_2881280 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P20809 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
IL-11 is a member of the interleukin family of cytokines. It was discovered in the late 20th century as researchers were exploring various cytokines involved in immune responses and cell growth regulation. IL-11 has significant effects on hematopoietic cells. It can stimulate the proliferation and differentiation of megakaryocytes, which are the precursors of platelets. This action helps in the regulation of platelet production.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for IL-11 antibody 55169-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Nat Commun ALKBH5-mediated m6A modification of IL-11 drives macrophage-to-myofibroblast transition and pathological cardiac fibrosis in mice | ||
Sci Adv Inhaled siRNA nanoparticles targeting IL11 inhibit lung fibrosis and improve pulmonary function post-bleomycin challenge.
| ||
Life Sci The effect of hepatic stellate cell derived-IL-11 on hepatocyte injury in hepatic fibrosis | ||
Ecotoxicol Environ Saf Carbon disulfide induced decidualization disorder in the mice uterus at the window of implantation. | ||
Vet Res Antiviral activity of interleukin-11 as a response to porcine epidemic diarrhea virus infection.
| ||
Theranostics IL11 signaling mediates piR-2158 suppression of cell stemness and angiogenesis in breast cancer |