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验证数据展示

  • Cytometric bead array standard curve of MP50135-1

    Cytometric bead array standard curve of MP50135-1

    Cytometric bead array standard curve of MP50135-1, IL7 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60206-2-PBS. Detection antibody: 60206-1-PBS. Standard:Ag16314. Range: 3.125-100 ng/mL.

IL-7 Monoclonal antibody, PBS Only (Detector)

IL-7 Monoclonal Antibody for Cytometric bead array, Indirect ELISA
Cat No. 60206-1-PBS

产品说明书

CloneNo. 5D5G7

宿主/亚型

Mouse / IgG2b

种属反应性

human

应用

Cytometric bead array, Indirect ELISA

别名

IL7, Interleukin-7, interleukin 7, IL 7, 5D5G7

缓冲液配方:  PBS Only
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

60206-1-PBS targets IL-7 as part of a matched antibody pair:

MP50135-1: 60206-2-PBS capture and 60206-1-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 Cytometric bead array, Indirect ELISA Application Description
经测试反应性 human
免疫原 IL-7 fusion protein Ag16314 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
亲和力
KD=7.40 x 10-10M
KOff=7.82 x 10-6M
KOn=1.06 x 104M
全称 interleukin 7
别名 IL7, Interleukin-7, interleukin 7, IL 7, 5D5G7
计算分子量 20 kDa
GenBank蛋白编号BC047698
基因名称 IL-7
Gene ID (NCBI) 3574
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP13232
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IL-7 is one of the members of IL-2 superfamily. IL-7 is a hematopoietic growth factor secreted by stromal cells in the bone marrow and thymus. It is also produced by keratinocytes, dendritic cells, hepatocytes, neurons, and epithelial cells, but is not produced by normal lymphocytes. IL7 plays an active role in the development, survival, maintaining and restoring homeostasis of mature T lymphocytes. It is also a key regulator of the commitment, survival, proliferation and maturation of B cells during development. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can be a potent inducer of proinflammatory cytokines and chemokines which may defend against the infection, but may also mediate destructive lung injury. Elevated serum IL7 levels, together with several other circulating cytokines and chemokines, has been found to be associated with the severity of Coronavirus Disease 19 (COVID-19).