验证数据展示
产品信息
25095-1-PBS targets IGFN1 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag18731 Product name: Recombinant human IGFN1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 42-385 aa of BC131529 Sequence: IYGERRDATRSSTSRYKPGTGSFSKDAQGPMGHFSQGLADMEVQPGEAATLSCTLTSDLGPGTWFKDGVKLTTQDGVIFKQDGLVHSLFITHVQGTQAGRYTFVAGDQQSEATLTVQDSPTIAPDVTEKLREPLVVKAGKPVIVKIPFQSHLPIQAAWRKDGAEVVGSSDREAQVDLGDGYTRLCLPSAGRKDCGQYSVTLRSEGGSVQAELTLQVIDKPDPPQGPMEVQDCHRAGVCLRWRPPRDNGGRTVECYVVERRQAGRSTWLKVGEAPADSTTFTDAHVEPGRKYTFRVRAVTSEGAGEALESEEILVAPEALPKAPSAPAILSASSQGITLTWTAPR 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | immunoglobulin-like and fibronectin type III domain containing 1 |
| 别名 | |
| 计算分子量 | 1251 aa, 138 kDa |
| 观测分子量 | 100 kDa |
| GenBank蛋白编号 | BC131529 |
| 基因名称 | IGFN1 |
| Gene ID (NCBI) | 91156 |
| RRID | AB_3669462 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q86VF2 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Immunoglobulin-like and fibronectin type III domain-containing protein 1 (IGFN1), also known as EEF1A2-binding protein 1 (EEF1A2BP1) or KY-interacting protein 1 (KYIP1), presents structural similarity to sarcomeric proteins belonging to the intracellular Ig superfamily, including myosin-binding protein C fast and slow-type skeletal muscle isoforms (PMID: 18756455). IGFN1 along with KY and FLNC is the part of a Z-band associated protein complex likely providing structural support to the skeletal muscle (PMID: 20206623). IGFN1 gene has been associated with some cancers (PMID: 28027327; 30335789; 35456975). At least five isoforms of IGFN1 produced by alternative splicing have been identified (PMID: 20206623).
