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验证数据展示

  • WB analysis of HeLa using 83002-4-RR (same clone as 83002-4-PBS)

    WB analysis of HeLa using 83002-4-RR (same clone as 83002-4-PBS)

    WB result of IFNAR1 antibody (83002-4-RR; 1:1200; incubated at room temperature for 1.5 hours) with sh-Control and sh-IFNAR1 transfected HeLa cells. This data was developed using the same antibody clone with 83002-4-PBS in a different storage buffer formulation.

  • WB analysis using 83002-4-RR (same clone as 83002-4-PBS)

    WB analysis using 83002-4-RR (same clone as 83002-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83002-4-RR (IFNAR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83002-4-PBS in a different storage buffer formulation.

  • FC experiment of Jurkat using 83002-4-RR (same clone as 83002-4-PBS)

    FC experiment of Jurkat using 83002-4-RR (same clone as 83002-4-PBS)

    1x10^6 Jurkat cells were surface stained with 0.25 ug IFNAR1 Recombinant antibody (83002-4-RR, Clone:230549C8) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)(red), or 0.25 ug Isotype Control (blue). Cells were not fixed. This data was developed using the same antibody clone with 83002-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83002-4-RR

    Affinity and Kinetic Characterization of 83002-4-RR

    Biolayer interferometry (BLl) kinetic assays of 83002-4-RR against Human IFNAR1 were performed. The affinity constant is 2.04 nM.

  • Featured Product
  • KD/KO验证
    • {{ptg:ProductFeaturesInfo}}

IFNAR1 Recombinant monoclonal antibody, PBS Only

IFNAR1 Uni-rAb® Recombinant Antibody for WB, FC, Indirect ELISA
Cat No. 83002-4-PBS

产品说明书

CloneNo. 230549C8

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, FC, Indirect ELISA

别名

230549C8, AVP, CRF2 1, CRF2-1, Cytokine receptor class-II member 1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

83002-4-PBS targets IFNAR1 in WB, FC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, FC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Eg0156

Product name: Recombinant Human IFNAR1 protein (Myc Tag, His Tag)

Source: mammalian cells-derived, pHZ-KIsec

Tag: Myc & 6*His

Domain: 28-436 aa of BC021825

Sequence: KNLKSPQKVEVDIIDDNFILRWNRSDESVGNVTFSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSFTPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVEERIENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSGNTPVIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSVFSDAVCEKTKPGNTSK

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 interferon (alpha, beta and omega) receptor 1
别名 230549C8, AVP, CRF2 1, CRF2-1, Cytokine receptor class-II member 1
计算分子量 557 aa, 64 kDa
观测分子量80-140 kDa
GenBank蛋白编号BC021825
基因名称 IFNAR1
Gene ID (NCBI) 3454
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDP17181
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Interferon alpha and beta receptor subunit 1 (IFNAR1) is a type I membrane protein that associates with IFNAR2 to form the receptor for type I interferons, including interferons-alpha, -beta, and -lambda. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2, and then increase transcription of the IFN-induced genes whose products exert antiviral, immunomodulatory, and antiproliferative effects.