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验证数据展示

  • FC experiment of mouse splenocytes using 98082-1-RR (same clone as 98082-1-PBS)

    FC experiment of mouse splenocytes using 98082-1-RR (same clone as 98082-1-PBS)

    1x10^6 mouse splenocytes were intracellularly stained with 0.25 ug Anti-Mouse IFN-beta Rabbit Recombinant Antibody (98082-1-RR, Clone:240230B6) or isotype control and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Cells were stained with CoraLite® Plus 647 Anti-Mouse CD19 before fixing. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98082-1-PBS in a different storage buffer formulation.

  • FC experiment of mouse splenocytes using 98082-1-RR (same clone as 98082-1-PBS)

    FC experiment of mouse splenocytes using 98082-1-RR (same clone as 98082-1-PBS)

    1x10^6 mouse splenocytes were intracellularly stained with 0.25 ug Anti-Mouse IFN-beta Rabbit Recombinant Antibody (98082-1-RR, Clone:240230B6)(red) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), or 0.25 ug Isotype Control(blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98082-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98082-1-RR

    Affinity and Kinetic Characterization of 98082-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98082-1-RR against Mouse IFN-beta were performed. The affinity constant is 1.91 nM.

Anti-Mouse IFN-beta Rabbit Recombinant Antibody, PBS Only

IFN-beta Uni-rAbTM Recombinant Antibody for FC (Intra)
Cat No. 98082-1-PBS

产品说明书

CloneNo. 240230B6

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC (Intra)

别名

Ifnb1, 240230B6, Ifb, IFN beta, IFNB

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

98082-1-PBS targets IFN-beta in FC (Intra) applications and shows reactivity with mouse samples.

经测试应用 FC (Intra) Application Description
经测试反应性 mouse
免疫原 IFN-beta fusion protein Eg0660 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 interferon beta 1, fibroblast
别名 Ifnb1, 240230B6, Ifb, IFN beta, IFNB
计算分子量22KD
GenBank蛋白编号NM_010510.1
基因名称 Ifnb1
Gene ID (NCBI) 15977
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP01575
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Interferon-beta (IFN-β) is a type I interferon, which is a group of signaling proteins made and released by host cells in response to the presence of several viruses, including double-stranded RNA produced by many viruses. IFN-β is a single protein species and is molecularly related to IFN-α subtypes, although it is antigenically distinct from them. It is mainly produced by fibroblasts and plays a crucial role in the innate immune response against viruses. IFN-β can inhibit viral replication by interfering with the virus's RNA or DNA, thus suppressing viral growth. It also enhances the cytotoxic activity of natural killer (NK) cells and promotes the expression of major histocompatibility complex (MHC) class I molecules.