验证数据展示
经过测试的应用
| Positive WB detected in | mouse kidney tissue, rat kidney tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
30530-1-AP targets IDO2 in WB, ELISA applications and shows reactivity with Human, mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | Human, mouse, rat |
| 免疫原 | IDO2 fusion protein Ag33013 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | indoleamine 2,3-dioxygenase 2 |
| 别名 | IDO 2, IDO2, INDOL1, indoleamine 2,3 dioxygenase 2 |
| 计算分子量 | 47 kDa |
| 观测分子量 | 40-47 kDa |
| GenBank蛋白编号 | NM_194294 |
| 基因名称 | IDO2 |
| Gene ID (NCBI) | 169355 |
| RRID | AB_3086352 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q6ZQW0 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
IDO2 is one of two closely related tryptophan catabolizing enzymes induced under inflammatory conditions. In contrast to the immunoregulatory role defined for IDO1 in cancer models, IDO2 has a proinflammatory function in models of autoimmunity and contact hypersensitivity. The product of the IDO2 gene is a 420 amino-acid protein, with a molecular weight of ~47 kDa. (PMID: 34965962, PMID: 29807576, PMID: 35493480)
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for IDO2 antibody 30530-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |