验证数据展示
产品信息
25053-1-AP targets IDO2 in WB, IHC, IF, ELISA applications and shows reactivity with human samples.
| 经测试应用 | ELISA Application Description |
| 文献引用应用 | WB, IHC, IF |
| 经测试反应性 | human |
| 文献引用反应性 | human, mouse |
| 免疫原 |
CatNo: Ag21866 Product name: Recombinant human IDO2 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-135 aa of BC113496 Sequence: MLHFHYYDTSNKIMEPHRPNVKTAVPLSLESYHISEEYGFLLPDSLKELPDHYRPWMEIANKLPQLIDAHQLQAHVDKMPLLSCQFLKGHREQRLAHLVLSFLTMGYVWQEGEAQPAEVLPRNLALPFVEVSRNL 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | indoleamine 2,3-dioxygenase 2 |
| 别名 | Indoleamine 2,3-dioxygenase 2, indoleamine 2,3 dioxygenase 2, INDOL1, IDO-2, IDO 2 |
| 计算分子量 | 407 aa, 45 kDa |
| 观测分子量 | 45 kDa |
| GenBank蛋白编号 | BC113496 |
| 基因名称 | IDO2 |
| Gene ID (NCBI) | 169355 |
| RRID | AB_2879872 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q6ZQW0 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
IDO2, also named as INDOL1, catalyzes the first and rate-limiting step in the kynurenine pathway of tryptophan catabolism. IDO2 gene has two isoforms with MW 45 kDa and 20 kDa.
发表文章
| Species | Application | Title |
|---|---|---|
Sci Signal Kynurenine signaling through the aryl hydrocarbon receptor maintains the undifferentiated state of human embryonic stem cells. | ||
Toxicol Appl Pharmacol Salinomycin promotes T-cell proliferation by inhibiting the expression and enzymatic activity of immunosuppressive indoleamine-2,3-dioxygenase in human breast cancer cells. | ||
FEBS J Indoleamine 2,3-dioxygenase 2 deficiency associates with autism-like behavior via dopaminergic neuronal dysfunction | ||
Cancer Med Tryptophan metabolism enzymes are potential targets in ovarian clear cell carcinoma |
