Recombinant Human SOST protein (His Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
His Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human SOST protein Gln24-Tyr213(Accession# Q9BQB4) with a His tag at the C-terminus. |
| 基因ID | 50964 |
| 蛋白编号 | Q9BQB4 |
| 预测分子量 | 25.9 kDa |
| SDS-PAGE | 35-40 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Sclerostin (Sost) is a potent negative regulator of bone mass, where it normally inhibits Wnt signaling through interactions with low‐density lipoprotein receptor‐related protein (LRP) 5/6 co‐receptors. Expression of the gene product sclerostin in bone is
参考文献:
1. van Bezooijen, et al. (2005) Biochemistry.16(3):319-327. 2. Chang Jiun C, et al. (2018) Biochemistry.33(6):1105-1113. 3. Sun Lisha, et al. (2022) Biochemistry.21(1):228.
